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OGDH dimer decarboxylates 2-OG Show undefined attributes

catalystActivity

[CatalystActivity:10427281] oxoglutarate dehydrogenase (succinyl-transferring) activity of OGDH complex [mitochondrial matrix]

category transition

compartment

[Compartment:5460] mitochondrial matrix

created [InstanceEdit:10424722] Weiser, Joel, 2025年08月27日

dbId 10427283

displayName OGDH dimer decarboxylates 2-OG

eventOf

[Pathway:R-SSC-9853506] OGDH complex synthesizes succinyl-CoA from 2-OG - Sus scrofa

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

inferredFrom

[Reaction:R-HSA-71401] OGDH dimer decarboxylates 2-OG - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

OGDH dimer decarboxylates 2-OG
2-oxoglutarate + H(+) + N(6)-((R)-lipoyl)-L-lysyl-(dihydrolipoyllysine-residue succinyltransferase) => CO2 + N(6)-((R)-S(8)-succinyldihydrolipoyl)-L-lysyl-(dihydrolipoyllysine-residue succinyltransferase)
Oxidative decarboxylation of alpha-ketoglutarate to succinyl CoA by alpha-ketoglutarate dehydrogenase

output

precedingEvent

regulatedBy

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49633] Sus scrofa

stId R-SSC-71401

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(precedingEvent)

(hasEvent)

[Pathway:R-SSC-9853506] OGDH complex synthesizes succinyl-CoA from 2-OG

(inferredTo)

[Reaction:R-HSA-71401] OGDH dimer decarboxylates 2-OG

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