Reactome Pathway Database

Schema > Reaction > Entries

DNA polymerases delta, epsilon or kappa bind the GG-NER site Show undefined attributes

category binding

compartment

[Compartment:7660] nucleoplasm

created [InstanceEdit:10424722] Weiser, Joel, 2025年08月27日

dbId 10503141

displayName DNA polymerases delta, epsilon or kappa bind the GG-NER site

eventOf

[Pathway:R-SSC-5696400] Dual Incision in GG-NER - Sus scrofa

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-SSC-5690988] 3'-incision of DNA by ERCC5 (XPG) in GG-NER - Sus scrofa

inferredFrom

[Reaction:R-HSA-5690213] DNA polymerases delta, epsilon or kappa bind the GG-NER site - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

DNA polymerases delta, epsilon or kappa bind the GG-NER site

output

[Complex:R-SSC-5690214] GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm]

precedingEvent

[Reaction:R-SSC-5690990] 5'- incision of DNA by ERCC1:ERCC4 in GG-NER - Sus scrofa

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49633] Sus scrofa

stId R-SSC-5690213

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SSC-5696400] Dual Incision in GG-NER

(precedingEvent)

[Reaction:R-SSC-5690988] 3'-incision of DNA by ERCC5 (XPG) in GG-NER

(inferredTo)

[Reaction:R-HSA-5690213] DNA polymerases delta, epsilon or kappa bind the GG-NER site

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