Reactome Pathway Database

Schema > Reaction > Entries

CD36 (FAT) translocates a long chain fatty acid from the extracellular region to the cytosol Show undefined attributes

catalystActivity

[CatalystActivity:10457712] long-chain fatty acid transmembrane transporter activity of 4xPalmC-CD36 [plasma membrane]

category transition

compartment

[Compartment:876] plasma membrane

created [InstanceEdit:10424722] Weiser, Joel, 2025年08月27日

dbId 10457714

displayName CD36 (FAT) translocates a long chain fatty acid from the extracellular region to the cytosol

eventOf

[Pathway:R-SSC-434313] Intracellular metabolism of fatty acids regulates insulin secretion - Sus scrofa

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-SSC-434382] ACSL3,4 ligates coenzyme A (CoA-SH) to a long chain fatty acid yielding fatty acyl-coenzyme A - Sus scrofa

inferredFrom

[Reaction:R-HSA-434381] CD36 (FAT) translocates a long chain fatty acid from the extracellular region to the cytosol - Homo sapiens

input

[SimpleEntity:R-ALL-8954142] LCFA(-) [extracellular region]

isInDisease false

isInferred true

maxDepth 1

name

CD36 (FAT) translocates a long chain fatty acid from the extracellular region to the cytosol
a long-chain fatty acid(out) = a long-chain fatty acid(in)

output

[SimpleEntity:R-ALL-8876730] LCFA(-) [cytosol]

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49633] Sus scrofa

stId R-SSC-434381

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SSC-434313] Intracellular metabolism of fatty acids regulates insulin secretion

(precedingEvent)

[Reaction:R-SSC-434382] ACSL3,4 ligates coenzyme A (CoA-SH) to a long chain fatty acid yielding fatty acyl-coenzyme A

(inferredTo)

[Reaction:R-HSA-434381] CD36 (FAT) translocates a long chain fatty acid from the extracellular region to the cytosol

© 2025 Reactome

Cite Us!