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Schema > Reaction > Entries

GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP Show undefined attributes

catalystActivity

[CatalystActivity:10490336] UDP-N-acetylglucosamine 2-epimerase activity of GNE hexamer [cytosol]

category transition

compartment

[Compartment:70101] cytosol

created [InstanceEdit:10424722] Weiser, Joel, 2025年08月27日

dbId 10490338

displayName GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP

eventOf

[Pathway:R-SSC-4085001] Sialic acid metabolism - Sus scrofa

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-SSC-4085028] GNE phosphorylates ManNAc to ManNAc-6-P - Sus scrofa

inferredFrom

[Reaction:R-HSA-4085021] GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP
GNE hydrolyzes, epimerises UDP-GlcNAc to ManNAc and UDP

output

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49633] Sus scrofa

stId R-SSC-4085021

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SSC-4085001] Sialic acid metabolism

(precedingEvent)

[Reaction:R-SSC-4085028] GNE phosphorylates ManNAc to ManNAc-6-P

(inferredTo)

[Reaction:R-HSA-4085021] GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP

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