Reactome Pathway Database

Schema > Reaction > Entries

NEU3 hydrolyzes Neu5Ac from glycoconjugates Show undefined attributes

catalystActivity

[CatalystActivity:10473724] exo-alpha-sialidase activity of NEU3 [plasma membrane]

category transition

compartment

created [InstanceEdit:10424722] Weiser, Joel, 2025年08月27日

dbId 10490326

displayName NEU3 hydrolyzes Neu5Ac from glycoconjugates

eventOf

[Pathway:R-SSC-4085001] Sialic acid metabolism - Sus scrofa

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-SSC-4085217] NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate - Sus scrofa

inferredFrom

[Reaction:R-HSA-4084994] NEU3 hydrolyzes Neu5Ac from glycoconjugates - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

NEU3 hydrolyzes Neu5Ac from glycoconjugates

output

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49633] Sus scrofa

stId R-SSC-4084994

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SSC-4085001] Sialic acid metabolism

(precedingEvent)

[Reaction:R-SSC-4085217] NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate

(inferredTo)

[Reaction:R-HSA-4084994] NEU3 hydrolyzes Neu5Ac from glycoconjugates

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