Reactome Pathway Database

Schema > Reaction > Entries

Caspase-mediated cleavage of Z0-2 Show undefined attributes

catalystActivity

[CatalystActivity:10444483] cysteine-type endopeptidase activity of Caspase-3 [cytosol]

category transition

compartment

[Compartment:876] plasma membrane

created [InstanceEdit:10424722] Weiser, Joel, 2025年08月27日

dbId 10448915

displayName Caspase-mediated cleavage of Z0-2

eventOf

[Pathway:R-SSC-351906] Apoptotic cleavage of cell adhesion proteins - Sus scrofa

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[Reaction:R-HSA-351871] Caspase-mediated cleavage of Z0-2 - Homo sapiens

input

[EntityWithAccessionedSequence:R-SSC-351862] TJP2 [plasma membrane]

isInDisease false

isInferred true

maxDepth 1

name

Caspase-mediated cleavage of Z0-2

output

[EntityWithAccessionedSequence:R-SSC-351897] TJP2 [plasma membrane]

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49633] Sus scrofa

stId R-SSC-351871

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SSC-351906] Apoptotic cleavage of cell adhesion proteins

(inferredTo)

[Reaction:R-HSA-351871] Caspase-mediated cleavage of Z0-2

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