Reactome Pathway Database

Schema > Reaction > Entries

CYP2C19 5-hydroxylates omeprazole Show undefined attributes

catalystActivity

[CatalystActivity:10447597] monooxygenase activity of Cytochrome P450 (CYP2C8 based) [endoplasmic reticulum membrane]

category transition

compartment

created [InstanceEdit:10424722] Weiser, Joel, 2025年08月27日

dbId 10447618

displayName CYP2C19 5-hydroxylates omeprazole

eventOf

[Pathway:R-SSC-211981] Xenobiotics - Sus scrofa

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[Reaction:R-HSA-211929] CYP2C19 5-hydroxylates omeprazole - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

CYP2C19 5-hydroxylates omeprazole

output

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49633] Sus scrofa

stId R-SSC-211929

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SSC-211981] Xenobiotics

(inferredTo)

[Reaction:R-HSA-211929] CYP2C19 5-hydroxylates omeprazole

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