Reactome Pathway Database

Schema > Reaction > Entries

ERK5 translocates to the nucleus Show undefined attributes

category transition

compartment

created [InstanceEdit:10424722] Weiser, Joel, 2025年08月27日

dbId 10442890

displayName ERK5 translocates to the nucleus

eventOf

[Pathway:R-SSC-198765] Signalling to ERK5 - Sus scrofa

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-SSC-198746] ERK1/2/5 activate RSK1/2/3 - Sus scrofa

inferredFrom

[Reaction:R-HSA-198714] ERK5 translocates to the nucleus - Homo sapiens

input

[EntityWithAccessionedSequence:R-SSC-198721] phospho-p-T218,Y221-MAPK7 [cytosol]

isInDisease false

isInferred true

maxDepth 1

name

ERK5 translocates to the nucleus

output

[EntityWithAccessionedSequence:R-SSC-198738] phospho-p-T218,Y221-MAPK7 [nucleoplasm]

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49633] Sus scrofa

stId R-SSC-198714

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SSC-198765] Signalling to ERK5

(precedingEvent)

[Reaction:R-SSC-198746] ERK1/2/5 activate RSK1/2/3

(inferredTo)

[Reaction:R-HSA-198714] ERK5 translocates to the nucleus

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