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Schema > Reaction > Entries

NAPRT1 dimer transfers PRIB to NCA to form NAMN Show undefined attributes

catalystActivity

[CatalystActivity:10442719] nicotinate phosphoribosyltransferase activity of NAPRT1 dimer [cytosol]

category transition

compartment

[Compartment:70101] cytosol

created [InstanceEdit:10424722] Weiser, Joel, 2025年08月27日

dbId 10442721

displayName NAPRT1 dimer transfers PRIB to NCA to form NAMN

eventOf

[Pathway:R-SSC-196807] Nicotinate metabolism - Sus scrofa

evidenceType [EvidenceType:9965817] inferred by electronic annotation

goBiologicalProcess [GO_BiologicalProcess:259346] NAD+ biosynthetic process via the salvage pathway

inferredFrom

[Reaction:R-HSA-197186] NAPRT1 dimer transfers PRIB to NCA to form NAMN - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

NAPRT1 dimer transfers PRIB to NCA to form NAMN
nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O => nicotinate beta-D-ribonucleotide + ADP + phosphate + diphosphate
A phosphoribosyl group is added to nicotinate to form nicotinate mononucleotide (NaMN)

output

precedingEvent

regulatedBy

[Requirement:R-HSA-2509853] Requirement by 'Mg2+ [cytosol]'

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49633] Sus scrofa

stId R-SSC-197186

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SSC-196807] Nicotinate metabolism

(inferredTo)

[Reaction:R-HSA-197186] NAPRT1 dimer transfers PRIB to NCA to form NAMN

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