Reactome Pathway Database

Schema > BlackBoxEvent > Entries

NLRP3 activation by small molecules Show undefined attributes

category omitted

compartment

[Compartment:70101] cytosol

created [InstanceEdit:10424722] Weiser, Joel, 2025年08月27日

dbId 10470128

displayName NLRP3 activation by small molecules

eventOf

[Pathway:R-SSC-844456] The NLRP3 inflammasome - Sus scrofa

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[BlackBoxEvent:R-HSA-1306876] NLRP3 activation by small molecules - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

NLRP3 activation by small molecules

output

precedingEvent

releaseDate 2025年09月18日

schemaClass BlackBoxEvent

species

[Species:49633] Sus scrofa

stId R-SSC-1306876

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SSC-844456] The NLRP3 inflammasome

(inferredTo)

[BlackBoxEvent:R-HSA-1306876] NLRP3 activation by small molecules

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