Reactome Pathway Database

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Nuclear signaling by ERBB4 Show undefined attributes

created [InstanceEdit:10424722] Weiser, Joel, 2025年08月27日

dbId 10539455

displayName Nuclear signaling by ERBB4

eventOf

[Pathway:R-SSC-1236394] Signaling by ERBB4 - Sus scrofa

evidenceType [EvidenceType:9965817] inferred by electronic annotation

hasDiagram false

hasEHLD false

hasEvent

[Reaction:R-SSC-1251997] Cleavage of ERBB4m80 by gamma-scretase complex - Sus scrofa
[BlackBoxEvent:R-SSC-1252013] Translocation of ERBB4s80 to the nucleus - Sus scrofa
[Reaction:R-SSC-1253343] WWOX binds ERBB4s80 - Sus scrofa
[Reaction:R-SSC-1254251] ERBB4s80 binds YAP1 - Sus scrofa
[BlackBoxEvent:R-SSC-1254248] Translocation of ERBB4s80:YAP1 complex to the nucleus - Sus scrofa
[Reaction:R-SSC-1254291] ERBB4s80 binds STAT5A - Sus scrofa
[BlackBoxEvent:R-SSC-1254285] ERBB4s80:STAT5A complex translocates to the nucleus - Sus scrofa
[Reaction:R-SSC-1254386] ERBB4s80 forms a complex with estrogen receptor ESR1 - Sus scrofa
[BlackBoxEvent:R-SSC-1254376] Translocation of cytosolic ERBB4s80 to mitochondrial matrix - Sus scrofa

inferredFrom

[Pathway:R-HSA-1251985] Nuclear signaling by ERBB4 - Homo sapiens

isInDisease false

isInferred true

maxDepth 2

name

Nuclear signaling by ERBB4

releaseDate 2025年09月18日

schemaClass Pathway

species

[Species:49633] Sus scrofa

stId R-SSC-1251985

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SSC-1236394] Signaling by ERBB4

(inferredTo)

[Pathway:R-HSA-1251985] Nuclear signaling by ERBB4

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