Reactome Pathway Database

Schema > BlackBoxEvent > Entries

Lyn activates ERK Show undefined attributes

catalystActivity

[CatalystActivity:10468261] non-membrane spanning protein tyrosine kinase activity of Growth Hormone:Growth Hormone Receptor-JAK2 dimer:LYN [plasma membrane]

category omitted

compartment

[Compartment:70101] cytosol

created [InstanceEdit:10424722] Weiser, Joel, 2025年08月27日

dbId 10468263

displayName Lyn activates ERK

eventOf

[Pathway:R-SSC-982772] Growth hormone receptor signaling - Sus scrofa

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[BlackBoxEvent:R-HSA-1168459] Lyn activates ERK - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

Lyn activates ERK

output

releaseDate 2025年09月18日

schemaClass BlackBoxEvent

species

[Species:49633] Sus scrofa

stId R-SSC-1168459

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SSC-982772] Growth hormone receptor signaling

(inferredTo)

[BlackBoxEvent:R-HSA-1168459] Lyn activates ERK

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