Reactome Pathway Database

Schema > Reaction > Entries

ABCB1 transports xenobiotics out of the cell Show undefined attributes

catalystActivity

[CatalystActivity:11028673] ATPase-coupled transmembrane transporter activity of ABCB1 [plasma membrane]

category transition

compartment

created [InstanceEdit:11001822] Weiser, Joel, 2025年08月28日

dbId 11028677

displayName ABCB1 transports xenobiotics out of the cell

eventOf

[Pathway:R-SPO-9757110] Prednisone ADME - Schizosaccharomyces pombe

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[Reaction:R-HSA-9659680] ABCB1 transports xenobiotics out of the cell - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

ABCB1 transports xenobiotics out of the cell

output

regulatedBy

[NegativeRegulation:11028678] Negative regulation by 'ABCB1:ABCB1 inhibitors [plasma membrane]'

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:68324] Schizosaccharomyces pombe

stId R-SPO-9659680

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SPO-9757110] Prednisone ADME

(inferredTo)

[Reaction:R-HSA-9659680] ABCB1 transports xenobiotics out of the cell

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