Reactome Pathway Database

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kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate Show undefined attributes

catalystActivity

[CatalystActivity:11012198] kynurenine-oxoglutarate transaminase activity of AADAT dimer [mitochondrial matrix]

category transition

compartment

[Compartment:5460] mitochondrial matrix

created [InstanceEdit:11001822] Weiser, Joel, 2025年08月28日

dbId 11012200

displayName kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate

eventOf

[Pathway:R-SPO-71240] Tryptophan catabolism - Schizosaccharomyces pombe

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[Reaction:R-HSA-893583] kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate
2-oxoglutarate + L-kynurenine => 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate

output

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:68324] Schizosaccharomyces pombe

stId R-SPO-893583

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SPO-71240] Tryptophan catabolism

(inferredTo)

[Reaction:R-HSA-893583] kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate

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