Reactome Pathway Database

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Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 Show undefined attributes

compartment

created [InstanceEdit:11001822] Weiser, Joel, 2025年08月28日

dbId 11032415

displayName Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3

eventOf

[Pathway:R-SPO-5625740] RHO GTPases activate PKNs - Schizosaccharomyces pombe

evidenceType [EvidenceType:9965817] inferred by electronic annotation

goBiologicalProcess [GO_BiologicalProcess:436782] regulation of androgen receptor signaling pathway

hasDiagram true

hasEHLD false

hasEvent

inferredFrom

[Pathway:R-HSA-5625886] Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 - Homo sapiens

isInDisease false

isInferred true

maxDepth 2

name

Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3

releaseDate 2025年09月18日

schemaClass Pathway

species

[Species:68324] Schizosaccharomyces pombe

stId R-SPO-5625886

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SPO-5625740] RHO GTPases activate PKNs

(inferredTo)

[Pathway:R-HSA-5625886] Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3

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