Reactome Pathway Database

Schema > Reaction > Entries

Trimerization of HSF1 in the nucleus Show undefined attributes

category binding

compartment

[Compartment:7660] nucleoplasm

created [InstanceEdit:11001822] Weiser, Joel, 2025年08月28日

dbId 11017128

displayName Trimerization of HSF1 in the nucleus

eventOf

[Pathway:R-SPO-3371511] HSF1 activation - Schizosaccharomyces pombe

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-SPO-5333051] RPA1 binds HSF1 - Schizosaccharomyces pombe

inferredFrom

[Reaction:R-HSA-5082391] Trimerization of HSF1 in the nucleus - Homo sapiens

input

3 × [EntityWithAccessionedSequence:R-SPO-5082385] hsf1 [nucleoplasm]

isInDisease false

isInferred true

maxDepth 1

name

Trimerization of HSF1 in the nucleus

output

[Complex:R-SPO-4793790] HSF1 trimer [nucleoplasm]

precedingEvent

[Reaction:R-SPO-5082409] Dissociation of HSF1:HSP90 complex in the nucleus - Schizosaccharomyces pombe

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:68324] Schizosaccharomyces pombe

stId R-SPO-5082391

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(precedingEvent)

[Reaction:R-SPO-5333051] RPA1 binds HSF1

(hasEvent)

[Pathway:R-SPO-3371511] HSF1 activation

(inferredTo)

[Reaction:R-HSA-5082391] Trimerization of HSF1 in the nucleus

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