Reactome Pathway Database

Schema > BlackBoxEvent > Entries

HSF1 trimer translocates to the nucleus Show undefined attributes

category omitted

compartment

created [InstanceEdit:11001822] Weiser, Joel, 2025年08月28日

dbId 11016323

displayName HSF1 trimer translocates to the nucleus

eventOf

[Pathway:R-SPO-3371511] HSF1 activation - Schizosaccharomyces pombe

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[BlackBoxEvent:R-HSA-3371527] HSF1 trimer translocates to the nucleus - Homo sapiens

input

[Complex:R-SPO-4793915] HSF1 trimer [cytosol]

isInDisease false

isInferred true

maxDepth 1

name

HSF1 trimer translocates to the nucleus

output

[Complex:R-SPO-4793790] HSF1 trimer [nucleoplasm]

precedingEvent

[Reaction:R-SPO-3371591] Trimerization of cytosolic HSF1 - Schizosaccharomyces pombe

regulatedBy

[NegativeRegulation:11016324] Negative regulation by 'YWHAE dimer [cytosol]'

releaseDate 2025年09月18日

schemaClass BlackBoxEvent

species

[Species:68324] Schizosaccharomyces pombe

stId R-SPO-3371527

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SPO-3371511] HSF1 activation

(inferredTo)

[BlackBoxEvent:R-HSA-3371527] HSF1 trimer translocates to the nucleus

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