Reactome Pathway Database

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AKT phosphorylates targets in the cytosol Show undefined attributes

compartment

[Compartment:70101] cytosol

created [InstanceEdit:11001822] Weiser, Joel, 2025年08月28日

dbId 11031767

displayName AKT phosphorylates targets in the cytosol

eventOf

[Pathway:R-SPO-1257604] PIP3 activates AKT signaling - Schizosaccharomyces pombe

evidenceType [EvidenceType:9965817] inferred by electronic annotation

goBiologicalProcess [GO_BiologicalProcess:172430] phosphatidylinositol 3-kinase/protein kinase B signal transduction

hasDiagram false

hasEHLD false

hasEvent

inferredFrom

[Pathway:R-HSA-198323] AKT phosphorylates targets in the cytosol - Homo sapiens

isInDisease false

isInferred true

maxDepth 2

name

AKT phosphorylates targets in the cytosol

releaseDate 2025年09月18日

schemaClass Pathway

species

[Species:68324] Schizosaccharomyces pombe

stId R-SPO-198323

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SPO-1257604] PIP3 activates AKT signaling

(inferredTo)

[Pathway:R-HSA-198323] AKT phosphorylates targets in the cytosol

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