Reactome Pathway Database

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Cleavage of adenine mispaired with 8-oxoguanine by MUTYH Show undefined attributes

catalystActivity

[CatalystActivity:11006415] DNA N-glycosylase activity of MUTYH:(8oxoG:Ade)-dsDNA [nucleoplasm]

category transition

compartment

[Compartment:7660] nucleoplasm

created [InstanceEdit:11001822] Weiser, Joel, 2025年08月28日

dbId 11006417

displayName Cleavage of adenine mispaired with 8-oxoguanine by MUTYH

eventOf

[Pathway:R-SPO-110331] Cleavage of the damaged purine - Schizosaccharomyces pombe

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[Reaction:R-HSA-110246] Cleavage of adenine mispaired with 8-oxoguanine by MUTYH - Homo sapiens

input

[Complex:R-SPO-110199] MUTYH:(8oxoG:Ade)-dsDNA [nucleoplasm]

isInDisease false

isInferred true

maxDepth 1

name

Cleavage of adenine mispaired with 8-oxoguanine by MUTYH

output

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:68324] Schizosaccharomyces pombe

stId R-SPO-110246

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SPO-110331] Cleavage of the damaged purine

(inferredTo)

[Reaction:R-HSA-110246] Cleavage of adenine mispaired with 8-oxoguanine by MUTYH

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