Reactome Pathway Database

Schema > Reaction > Entries

AKT binds PDPK1 Show undefined attributes

category binding

compartment

[Compartment:876] plasma membrane

created [InstanceEdit:11033291] Weiser, Joel, 2025年08月28日

dbId 11046737

displayName AKT binds PDPK1

eventOf

[Pathway:R-SCE-5218920] VEGFR2 mediated vascular permeability - Saccharomyces cerevisiae
[Pathway:R-SCE-389357] CD28 dependent PI3K/Akt signaling - Saccharomyces cerevisiae
[Pathway:R-SCE-1257604] PIP3 activates AKT signaling - Saccharomyces cerevisiae

evidenceType [EvidenceType:9965817] inferred by electronic annotation

goBiologicalProcess [GO_BiologicalProcess:262252] activation of protein kinase B activity

inferredFrom

[Reaction:R-HSA-2317314] AKT binds PDPK1 - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

AKT binds PDPK1

output

[Complex:R-SCE-2317313] p-S-AKT:PDPK1:PIP3 [plasma membrane]

precedingEvent

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:68322] Saccharomyces cerevisiae

stId R-SCE-2317314

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

(inferredTo)

[Reaction:R-HSA-2317314] AKT binds PDPK1

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