Reactome Pathway Database

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Signaling by the B Cell Receptor (BCR) Show undefined attributes

compartment

created [InstanceEdit:10084857] Weiser, Joel, 2025年08月27日

dbId 10198927

displayName Signaling by the B Cell Receptor (BCR)

eventOf

[Pathway:R-RNO-1280218] Adaptive Immune System - Rattus norvegicus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

hasDiagram true

hasEHLD false

hasEvent

[Pathway:R-RNO-983695] Antigen activates B Cell Receptor (BCR) leading to generation of second messengers - Rattus norvegicus
[Pathway:R-RNO-1168372] Downstream signaling events of B Cell Receptor (BCR) - Rattus norvegicus
[Pathway:R-RNO-5690714] CD22 mediated BCR regulation - Rattus norvegicus

inferredFrom

[Pathway:R-HSA-983705] Signaling by the B Cell Receptor (BCR) - Homo sapiens

isInDisease false

isInferred true

maxDepth 4

name

Signaling by the B Cell Receptor (BCR)
B Cell Activation

releaseDate 2025年09月18日

schemaClass Pathway

species

[Species:48895] Rattus norvegicus

stId R-RNO-983705

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-RNO-1280218] Adaptive Immune System

(hasEncapsulatedEvent)

(inferredTo)

[Pathway:R-HSA-983705] Signaling by the B Cell Receptor (BCR)

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