Reactome Pathway Database

Schema > Reaction > Entries

NLRX1 binds CHUK:IKBKB:IKBKG Show undefined attributes

category binding

compartment

created [InstanceEdit:10084857] Weiser, Joel, 2025年08月27日

dbId 10190847

displayName NLRX1 binds CHUK:IKBKB:IKBKG

eventOf

[Pathway:R-RNO-9758274] Regulation of NF-kappa B signaling - Rattus norvegicus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

goBiologicalProcess [GO_BiologicalProcess:162165] negative regulation of canonical NF-kappaB signal transduction

inferredFrom

[Reaction:R-HSA-9749471] NLRX1 binds CHUK:IKBKB:IKBKG - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

NLRX1 binds CHUK:IKBKB:IKBKG
NLRX1 binds activated IKK complex

output

[Complex:R-RNO-9749472] CHUK:IKBKB:IKBKG:K63polyUb-NLRX1 [cytosol]

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:48895] Rattus norvegicus

stId R-RNO-9749471

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-RNO-9758274] Regulation of NF-kappa B signaling

(inferredTo)

[Reaction:R-HSA-9749471] NLRX1 binds CHUK:IKBKB:IKBKG

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