Reactome Pathway Database

Schema > Reaction > Entries

ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 Show undefined attributes

catalystActivity

[CatalystActivity:10142603] arachidonate 12(S)-lipoxygenase activity of ALOX12:Fe2+ [cytosol]

category transition

compartment

[Compartment:70101] cytosol

created [InstanceEdit:10084857] Weiser, Joel, 2025年08月27日

dbId 10186232

displayName ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6

eventOf

[Pathway:R-RNO-9025106] Biosynthesis of DPAn-6 SPMs - Rattus norvegicus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[Reaction:R-HSA-9025957] ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6

output

[SimpleEntity:R-ALL-9025960] 14(S)-HDPAn-6 [cytosol]

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:48895] Rattus norvegicus

stId R-RNO-9025957

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-RNO-9025106] Biosynthesis of DPAn-6 SPMs

(inferredTo)

[Reaction:R-HSA-9025957] ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6

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