Reactome Pathway Database

Schema > Reaction > Entries

Beta-catenin displaces TLE:HDAC1 from TCF/LEF Show undefined attributes

category dissociation

compartment

[Compartment:7660] nucleoplasm

created [InstanceEdit:10084857] Weiser, Joel, 2025年08月27日

dbId 10148631

displayName Beta-catenin displaces TLE:HDAC1 from TCF/LEF

eventOf

[Pathway:R-RNO-201722] Formation of the beta-catenin:TCF transactivating complex - Rattus norvegicus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

inferredFrom

[Reaction:R-HSA-3299569] Beta-catenin displaces TLE:HDAC1 from TCF/LEF - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

Beta-catenin displaces TLE:HDAC1 from TCF/LEF

output

precedingEvent

[BlackBoxEvent:R-RNO-201669] Beta-catenin translocates to the nucleus - Rattus norvegicus

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:48895] Rattus norvegicus

stId R-RNO-3299569

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-RNO-201722] Formation of the beta-catenin:TCF transactivating complex

(precedingEvent)

(inferredTo)

[Reaction:R-HSA-3299569] Beta-catenin displaces TLE:HDAC1 from TCF/LEF

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