Reactome Pathway Database

Schema > Reaction > Entries

COQ6 hydroxylates DHB Show undefined attributes

catalystActivity

[CatalystActivity:10142711] oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen of COQ3:COQ4:COQ5:COQ6:COQ7:COQ9 [mitochondrial inner membrane]

category transition

compartment

created [InstanceEdit:10084857] Weiser, Joel, 2025年08月27日

dbId 10142725

displayName COQ6 hydroxylates DHB

eventOf

[Pathway:R-RNO-2142789] Ubiquinol biosynthesis - Rattus norvegicus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-RNO-2162193] COQ3 methylates DHDB - Rattus norvegicus

inferredFrom

[Reaction:R-HSA-2162187] COQ6 hydroxylates DHB - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

COQ6 hydroxylates DHB
DHB is hydroxylated to DHDB by COQ6

output

precedingEvent

[Reaction:R-RNO-2162192] COQ2 ligates all-E-10PrP2 to PHB - Rattus norvegicus

regulatedBy

[Requirement:10142726] Requirement by 'COQ8A,B:COQ6 [mitochondrial inner membrane]'

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:48895] Rattus norvegicus

stId R-RNO-2162187

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-RNO-2142789] Ubiquinol biosynthesis

(precedingEvent)

[Reaction:R-RNO-2162193] COQ3 methylates DHDB

(inferredTo)

[Reaction:R-HSA-2162187] COQ6 hydroxylates DHB

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