Reactome Pathway Database

Schema > Reaction > Entries

Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA Show undefined attributes

catalystActivity

[CatalystActivity:10141082] omega-6 fatty acid desaturase activity of FADS1 [endoplasmic reticulum membrane]

category transition

compartment

created [InstanceEdit:10084857] Weiser, Joel, 2025年08月27日

dbId 10141084

displayName Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA

eventOf

[Pathway:R-RNO-2046106] alpha-linolenic acid (ALA) metabolism - Rattus norvegicus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-RNO-2046100] Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA - Rattus norvegicus

inferredFrom

[Reaction:R-HSA-2046089] Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA

output

precedingEvent

[Reaction:R-RNO-2046088] Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA - Rattus norvegicus

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:48895] Rattus norvegicus

stId R-RNO-2046089

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-RNO-2046106] alpha-linolenic acid (ALA) metabolism

(precedingEvent)

[Reaction:R-RNO-2046100] Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA

(inferredTo)

[Reaction:R-HSA-2046089] Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA

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