Reactome Pathway Database

Schema > Reaction > Entries

PANK1/3 phosphorylate PanK Show undefined attributes

catalystActivity

[CatalystActivity:10104064] pantothenate kinase activity of PANK1/3 [cytosol]

category transition

compartment

[Compartment:70101] cytosol

created [InstanceEdit:10084857] Weiser, Joel, 2025年08月27日

dbId 10104066

displayName PANK1/3 phosphorylate PanK

eventOf

[Pathway:R-RNO-196783] Coenzyme A biosynthesis - Rattus norvegicus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

inferredFrom

[Reaction:R-HSA-199203] PANK1/3 phosphorylate PanK - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

PANK1/3 phosphorylate PanK
(R)-pantothenate + ATP => (R)-4'-phosphopantothenate + ADP + H(+)
Pantothenate is phosphorylated [PANK1;3;4]

output

precedingEvent

[Reaction:R-RNO-199206] SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol - Rattus norvegicus

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:48895] Rattus norvegicus

stId R-RNO-199203

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-RNO-196783] Coenzyme A biosynthesis

(precedingEvent)

(inferredTo)

[Reaction:R-HSA-199203] PANK1/3 phosphorylate PanK

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