Reactome Pathway Database

Schema > Reaction > Entries

ACAT1 tetramer acetylates IDH2 dimer Show undefined attributes

catalystActivity

[CatalystActivity:11083472] acetyltransferase activity of ACAT1 tetramer [mitochondrial matrix]

category transition

compartment

[Compartment:5460] mitochondrial matrix

created [InstanceEdit:11064438] Weiser, Joel, 2025年08月28日

dbId 11083474

displayName ACAT1 tetramer acetylates IDH2 dimer

eventOf

[Pathway:R-PFA-9854311] Maturation of TCA enzymes and regulation of TCA cycle - Plasmodium falciparum

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[Reaction:R-HSA-9854415] ACAT1 tetramer acetylates IDH2 dimer - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

ACAT1 tetramer acetylates IDH2 dimer

output

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:170928] Plasmodium falciparum

stId R-PFA-9854415

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-PFA-9854311] Maturation of TCA enzymes and regulation of TCA cycle

(inferredTo)

[Reaction:R-HSA-9854415] ACAT1 tetramer acetylates IDH2 dimer

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