Reactome Pathway Database

Schema > Reaction > Entries

p-S-Itga5:Itgb1 binds p-S373-Gja1 Show undefined attributes

authored

[InstanceEdit:9857469] May, Bruce, 2024年01月05日

category binding

compartment

[Compartment:876] plasma membrane

created [InstanceEdit:9857688] May, Bruce, 2024年01月08日

dbId 9857679

displayName p-S-Itga5:Itgb1 binds p-S373-Gja1

edited

[InstanceEdit:9857469] May, Bruce, 2024年01月05日

input

isChimeric false

isInDisease false

isInferred false

literatureReference

[LiteratureReference:9857659] Direct regulation of osteocytic connexin 43 hemichannels through AKT kinase activated by mechanical stimulation
[LiteratureReference:9857640] Mechanical stress-activated integrin ?5?1 induces opening of connexin 43 hemichannels
[LiteratureReference:9860499] "INTEGRINating" the connexin hemichannel function in bone osteocytes through the action of integrin ?5

maxDepth 1

modified [InstanceEdit:9927250] May, Bruce, 2024年11月05日

name

p-S-Itga5:Itgb1 binds p-S373-Gja1

orthologousEvent

[Reaction:R-HSA-9857703] p-S-ITGA5:ITGB1 binds p-S373-GJA1 - Homo sapiens

output

[Complex:R-MMU-9857694] p-S373-Gja1:p-S-Itga5:Itgb1 [plasma membrane]

releaseDate 2024年12月04日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

schemaClass Reaction

species

[Species:48892] Mus musculus

stId R-MMU-9857679

summation

[Summation:9907613] Phosphorylation of integrin alpha5 (Itga5) and Connexin 43 (...

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