Reactome Pathway Database

Schema > Reaction > Entries

IRAK1 phosphorylates Pellino Show undefined attributes

catalystActivity

[CatalystActivity:10004020] protein kinase activity of TRAF6:hp-IRAK1:Pellino [plasma membrane]

category transition

compartment

created [InstanceEdit:9965813] Weiser, Joel, 2025年08月27日

dbId 10004022

displayName IRAK1 phosphorylates Pellino

eventOf

[Pathway:R-MMU-937039] IRAK1 recruits IKK complex - Mus musculus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-MMU-937050] Pellino ubiquitinates hp-IRAK1 - Mus musculus

inferredFrom

[Reaction:R-HSA-937034] IRAK1 phosphorylates Pellino - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

IRAK1 phosphorylates Pellino

output

precedingEvent

[Reaction:R-MMU-937044] Pellino binds hp-IRAK1:TRAF6 - Mus musculus

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:48892] Mus musculus

stId R-MMU-937034

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-MMU-937039] IRAK1 recruits IKK complex

(precedingEvent)

[Reaction:R-MMU-937050] Pellino ubiquitinates hp-IRAK1

(inferredTo)

[Reaction:R-HSA-937034] IRAK1 phosphorylates Pellino

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