Reactome Pathway Database

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2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates Show undefined attributes

category dissociation

compartment

[Compartment:70101] cytosol

created [InstanceEdit:9965813] Weiser, Joel, 2025年08月27日

dbId 10065695

displayName 2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates

eventOf

[Pathway:R-MMU-3299685] Detoxification of Reactive Oxygen Species - Mus musculus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-MMU-3299753] CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 - Mus musculus

inferredFrom

[Reaction:R-HSA-8951723] 2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates - Homo sapiens

input

[Complex:R-MMU-8951722] 2xSOD1:CCS:Zn2+:2xCu1+ dimer [cytosol]

isInDisease false

isInferred true

maxDepth 1

name

2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates

output

2 × [Complex:R-MMU-3299706] CCS:Zn2+:2xCu1+:SOD1:Zn2+ [cytosol]

precedingEvent

[Reaction:R-MMU-3697860] SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+ - Mus musculus

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:48892] Mus musculus

stId R-MMU-8951723

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-MMU-3299685] Detoxification of Reactive Oxygen Species

(precedingEvent)

[Reaction:R-MMU-3299753] CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1

(inferredTo)

[Reaction:R-HSA-8951723] 2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates

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