Reactome Pathway Database

Schema > Reaction > Entries

LIG3-mediated DNA ligation via the single-nucleotide replacement pathway Show undefined attributes

catalystActivity

[CatalystActivity:9969830] DNA ligase activity of LIG3:XRCC1:POLB:SSB-dsDNA [nucleoplasm]

category transition

compartment

[Compartment:7660] nucleoplasm

created [InstanceEdit:9965813] Weiser, Joel, 2025年08月27日

dbId 9969832

displayName LIG3-mediated DNA ligation via the single-nucleotide replacement pathway

eventOf

[Pathway:R-MMU-110381] Resolution of AP sites via the single-nucleotide replacement pathway - Mus musculus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[Reaction:R-HSA-73931] LIG3-mediated DNA ligation via the single-nucleotide replacement pathway - Homo sapiens

input

[Complex:R-MMU-110341] LIG3:XRCC1:POLB:SSB-dsDNA [nucleoplasm]

isInDisease false

isInferred true

maxDepth 1

name

LIG3-mediated DNA ligation via the single-nucleotide replacement pathway

output

[Complex:R-MMU-110343] LIG3:XRCC1:POLB:dsDNA [nucleoplasm]

precedingEvent

[Reaction:R-MMU-73932] Resynthesis of excised residue by POLB - Mus musculus

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:48892] Mus musculus

stId R-MMU-73931

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-MMU-110381] Resolution of AP sites via the single-nucleotide replacement pathway

(inferredTo)

[Reaction:R-HSA-73931] LIG3-mediated DNA ligation via the single-nucleotide replacement pathway

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