Reactome Pathway Database

Schema > Reaction > Entries

alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ Show undefined attributes

catalystActivity

[CatalystActivity:9967691] L-aminoadipate-semialdehyde dehydrogenase activity of ALDH7A1 tetramer [mitochondrial matrix]

category transition

compartment

[Compartment:5460] mitochondrial matrix

created [InstanceEdit:9965813] Weiser, Joel, 2025年08月27日

dbId 9967693

displayName alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+

eventOf

[Pathway:R-MMU-71064] Lysine catabolism - Mus musculus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-MMU-70952] alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate - Mus musculus

inferredFrom

[Reaction:R-HSA-70941] alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+
(S)-2-amino-6-oxohexanoate + H2O + NAD(+) => 2 H(+) + L-2-aminoadipate + NADH

output

precedingEvent

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:48892] Mus musculus

stId R-MMU-70941

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-MMU-71064] Lysine catabolism

(precedingEvent)

[Reaction:R-MMU-70952] alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate

(inferredTo)

[Reaction:R-HSA-70941] alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+

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