Reactome Pathway Database

Schema > Reaction > Entries

Activated FGFR3 binds FRS2 Show undefined attributes

category binding

compartment

created [InstanceEdit:9965813] Weiser, Joel, 2025年08月27日

dbId 10040626

displayName Activated FGFR3 binds FRS2

eventOf

[Pathway:R-MMU-5654706] FRS-mediated FGFR3 signaling - Mus musculus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-MMU-5654408] Activated FGFR3 phosphorylates FRS2 - Mus musculus

inferredFrom

[Reaction:R-HSA-5654409] Activated FGFR3 binds FRS2 - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

Activated FGFR3 binds FRS2

output

[Complex:R-MMU-5654180] Activated FGFR3:FRS2 [plasma membrane]

precedingEvent

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:48892] Mus musculus

stId R-MMU-5654409

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-MMU-5654706] FRS-mediated FGFR3 signaling

(precedingEvent)

[Reaction:R-MMU-5654408] Activated FGFR3 phosphorylates FRS2

(inferredTo)

[Reaction:R-HSA-5654409] Activated FGFR3 binds FRS2

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