Reactome Pathway Database

Schema > Polymerisation > Entries

RIPK1:RIPK3 oligomerizes to form amyloid-like fibrils Show undefined attributes

category transition

compartment

[Compartment:70101] cytosol

created [InstanceEdit:9965813] Weiser, Joel, 2025年08月27日

dbId 10035659

displayName RIPK1:RIPK3 oligomerizes to form amyloid-like fibrils

eventOf

[Pathway:R-MMU-5213460] RIPK1-mediated regulated necrosis - Mus musculus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-MMU-5218891] RIPK1:RIPK3 oligomer binds MLKL - Mus musculus

inferredFrom

[Polymerisation:R-HSA-5218905] RIPK1:RIPK3 oligomerizes to form amyloid-like fibrils - Homo sapiens

input

[Complex:R-MMU-5218870] p-S166-RIPK1:p-S199,227-RIPK3 [cytosol]

isInDisease false

isInferred true

maxDepth 1

name

RIPK1:RIPK3 oligomerizes to form amyloid-like fibrils

output

[Polymer:R-MMU-5218908] p-S-RIPK1:p-S199,227-RIPK3 oligomer [cytosol]

precedingEvent

releaseDate 2025年09月18日

schemaClass Polymerisation

species

[Species:48892] Mus musculus

stId R-MMU-5218905

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-MMU-5213460] RIPK1-mediated regulated necrosis

(precedingEvent)

[Reaction:R-MMU-5218891] RIPK1:RIPK3 oligomer binds MLKL

(inferredTo)

[Polymerisation:R-HSA-5218905] RIPK1:RIPK3 oligomerizes to form amyloid-like fibrils

© 2025 Reactome

Cite Us!