Reactome Pathway Database

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Organic anion transport by SLC5/17/25 transporters Show undefined attributes

created [InstanceEdit:9965813] Weiser, Joel, 2025年08月27日

dbId 10080922

displayName Organic anion transport by SLC5/17/25 transporters

eventOf

[Pathway:R-MMU-9955298] SLC-mediated transport of organic anions - Mus musculus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

hasDiagram false

hasEHLD false

hasEvent

[Reaction:R-MMU-429749] SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol - Mus musculus
[Reaction:R-MMU-1614546] Sulfate is exported to the cytosol in exchange for dicarboxylate - Mus musculus
[Reaction:R-MMU-8876312] SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol - Mus musculus
[Reaction:R-MMU-428585] SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol - Mus musculus
[Reaction:R-MMU-372843] SLC25A10 mediates exchange of malate and phosphate - Mus musculus
[Reaction:R-MMU-75849] SLC25A1 exchanges CIT and MAL - Mus musculus
[Reaction:R-MMU-372449] SLC25A1 may exchange mitochondrial PEP for cytosolic anion - Mus musculus
[Reaction:R-MMU-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane - Mus musculus

inferredFrom

[Pathway:R-HSA-428643] Organic anion transport by SLC5/17/25 transporters - Homo sapiens

isInDisease false

isInferred true

maxDepth 2

name

Organic anion transport by SLC5/17/25 transporters

releaseDate 2025年09月18日

schemaClass Pathway

species

[Species:48892] Mus musculus

stId R-MMU-428643

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-MMU-9955298] SLC-mediated transport of organic anions

(inferredTo)

[Pathway:R-HSA-428643] Organic anion transport by SLC5/17/25 transporters

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