Reactome Pathway Database

Schema > Reaction > Entries

FMO1:FAD N-oxidises TAM Show undefined attributes

catalystActivity

[CatalystActivity:9988379] N,N-dimethylaniline monooxygenase activity of FMO1:FAD [endoplasmic reticulum membrane]

category transition

compartment

[Compartment:17960] smooth endoplasmic reticulum

created [InstanceEdit:9965813] Weiser, Joel, 2025年08月27日

dbId 9988381

displayName FMO1:FAD N-oxidises TAM

eventOf

[Pathway:R-MMU-217271] FMO oxidises nucleophiles - Mus musculus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[Reaction:R-HSA-217255] FMO1:FAD N-oxidises TAM - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

FMO1:FAD N-oxidises TAM
FMO1 N-oxidizes the anti-cancer drug tamoxifen

output

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:48892] Mus musculus

stId R-MMU-217255

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-MMU-217271] FMO oxidises nucleophiles

(inferredTo)

[Reaction:R-HSA-217255] FMO1:FAD N-oxidises TAM

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