Reactome Pathway Database

Schema > Reaction > Entries

beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP Show undefined attributes

catalystActivity

[CatalystActivity:9980116] steroid sulfotransferase activity of SULT1E1 dimer [cytosol]

category transition

compartment

[Compartment:70101] cytosol

created [InstanceEdit:9965813] Weiser, Joel, 2025年08月27日

dbId 9980118

displayName beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP

eventOf

[Pathway:R-MMU-156584] Cytosolic sulfonation of small molecules - Mus musculus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-MMU-176606] Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate - Mus musculus

inferredFrom

[Reaction:R-HSA-176521] beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP

output

precedingEvent

[Reaction:R-MMU-174389] PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS - Mus musculus

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:48892] Mus musculus

stId R-MMU-176521

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-MMU-156584] Cytosolic sulfonation of small molecules

(precedingEvent)

[Reaction:R-MMU-176606] Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate

(inferredTo)

[Reaction:R-HSA-176521] beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP

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