Reactome Pathway Database

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Toll Like Receptor TLR1:TLR2 Cascade Show undefined attributes

created [InstanceEdit:9965813] Weiser, Joel, 2025年08月27日

dbId 10081472

displayName Toll Like Receptor TLR1:TLR2 Cascade

eventOf

[Pathway:R-MMU-181438] Toll Like Receptor 2 (TLR2) Cascade - Mus musculus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

goBiologicalProcess [GO_BiologicalProcess:2266270] toll-like receptor TLR1:TLR2 signaling pathway

hasDiagram false

hasEHLD false

hasEvent

[Pathway:R-MMU-166058] MyD88:MAL(TIRAP) cascade initiated on plasma membrane - Mus musculus

inferredFrom

[Pathway:R-HSA-168179] Toll Like Receptor TLR1:TLR2 Cascade - Homo sapiens

isInDisease false

isInferred true

maxDepth 7

name

Toll Like Receptor TLR1:TLR2 Cascade

releaseDate 2025年09月18日

schemaClass Pathway

species

[Species:48892] Mus musculus

stId R-MMU-168179

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-MMU-181438] Toll Like Receptor 2 (TLR2) Cascade

(inferredTo)

[Pathway:R-HSA-168179] Toll Like Receptor TLR1:TLR2 Cascade

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