Reactome Pathway Database

Schema > Reaction > Entries

GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) Show undefined attributes

catalystActivity

[CatalystActivity:9976074] gamma-glutamyl carboxylase activity of GGCX [endoplasmic reticulum membrane]

category transition

compartment

created [InstanceEdit:9965813] Weiser, Joel, 2025年08月27日

dbId 9976166

displayName GGCX gamma-carboxylates F2(25-622) (pro-prothrombin)

eventOf

[Pathway:R-MMU-159740] Gamma-carboxylation of protein precursors - Mus musculus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

inferredFrom

[Reaction:R-HSA-159826] GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

GGCX gamma-carboxylates F2(25-622) (pro-prothrombin)
pro-prothrombin, uncarboxylated + 10 CO2 + 10 O2 + 10 vitamin K hydroquinone -> pro-prothrombin + 10 H2O + 10 vitamin K epoxide

output

precedingEvent

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:48892] Mus musculus

stId R-MMU-159826

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-MMU-159740] Gamma-carboxylation of protein precursors

(precedingEvent)

(inferredTo)

[Reaction:R-HSA-159826] GGCX gamma-carboxylates F2(25-622) (pro-prothrombin)

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