Reactome Pathway Database

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miR-21 RISC binds DNMT1 mRNA Show undefined attributes

authored

[InstanceEdit:9851210] Rothfels, Karen, 2023年10月14日

category binding

compartment

[Compartment:70101] cytosol

created [InstanceEdit:9851146] Rothfels, Karen, 2023年10月12日

crossReference

[DatabaseIdentifier:11944892] Mondo:0004992

dbId 9851147

disease

[Disease:1500689] cancer

displayName miR-21 RISC binds DNMT1 mRNA

edited

[InstanceEdit:9851215] Rothfels, Karen, 2023年10月14日

eventOf

[Pathway:R-HSA-9725371] Nuclear events stimulated by ALK signaling in cancer - Homo sapiens

followingEvent

[BlackBoxEvent:R-HSA-9851145] Translation of DNMT1 mRNA is repressed by miR-21 - Homo sapiens

input

isChimeric false

isInDisease true

isInferred false

literatureReference

maxDepth 1

modified [InstanceEdit:9852942] Rothfels, Karen, 2023年11月08日

name

miR-21 RISC binds DNMT1 mRNA

output

[Complex:R-HSA-9850915] miR-21 RISC:DNMT1 mRNA [cytosol]

precedingEvent

[BlackBoxEvent:R-HSA-9851139] STAT3-dependent MIR-21 gene expression - Homo sapiens

releaseDate 2023年12月06日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:9852935] Turner, Suzanne, 2023年11月08日

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-9851147

summation

[Summation:9850808] Translation of DNMT1 mRNA is negatively regulated by miR-21 ...

Referrals

(precedingEvent)

[BlackBoxEvent:R-HSA-9851145] Translation of DNMT1 mRNA is repressed by miR-21

(hasEvent)

[Pathway:R-HSA-9725371] Nuclear events stimulated by ALK signaling in cancer

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