Reactome Pathway Database

Schema > BlackBoxEvent > Entries

NPAS4 represses INS gene expression Show undefined attributes

authored

[InstanceEdit:9770624] Orlic-Milacic, Marija, 2022年04月08日

category omitted

compartment

created [InstanceEdit:9769305] Orlic-Milacic, Marija, 2022年03月16日

dbId 9769307

displayName NPAS4 represses INS gene expression

edited

[InstanceEdit:9795246] Orlic-Milacic, Marija, 2022年08月02日

eventOf

[Pathway:R-HSA-9768919] NPAS4 regulates expression of target genes - Homo sapiens

inferredFrom

[BlackBoxEvent:R-MMU-9770101] Npas4 represses Ins gene expression - Mus musculus

input

[EntityWithAccessionedSequence:R-HSA-8931792] INS gene [nucleoplasm]

isChimeric false

isInDisease false

isInferred true

maxDepth 1

modified [InstanceEdit:9830342] Matthews, Lisa, 2023年03月08日

name

NPAS4 represses INS gene expression

output

[EntityWithAccessionedSequence:R-HSA-264893] INS(25-110) [endoplasmic reticulum lumen]

precedingEvent

[Reaction:R-HSA-9769302] NPAS4 binds INS gene promoter - Homo sapiens

regulatedBy

[NegativeGeneExpressionRegulation:9770110] Negative gene expression regulation by '(NPAS4:ARNTL,NPAS4:ARNT,NPAS4:ARNT2):INS gene [nucleoplasm]'

releaseDate 2022年09月14日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:9795249] Lin, Yingxi, 2022年07月29日

schemaClass BlackBoxEvent

species

[Species:48887] Homo sapiens

stId R-HSA-9769307

summation

[Summation:9770102] Based on a study conducted in a mouse pancreatic beta cell-d...

Referrals

(hasEvent)

[Pathway:R-HSA-9768919] NPAS4 regulates expression of target genes

(inferredTo)

[BlackBoxEvent:R-MMU-9770101] Npas4 represses Ins gene expression

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