Reactome | keratinocyte of granulosum layer of epidermis

cellType

[CellType:9725588] keratinocyte

consumedByEvent

[CellDevelopmentStep:R-HSA-9727355] Keratinocyte of granulosum layer differentiates into corneocyte of corneum layer in interfollicular epidermis - Homo sapiens

created [InstanceEdit:9727356] Orlic-Milacic, Marija, 2021年04月16日

dbId 9727357

displayName keratinocyte of granulosum layer of epidermis

inDisease false

markerReference

[MarkerReference:9727989] "Activated" keratinocyte phenotype is unifying feature in conditions which predispose to squamous cell carcinoma of the skin
[MarkerReference:9824052] The small proline-rich proteins constitute a multigene family of differentially regulated cornified cell envelope precursor proteins
[MarkerReference:9839511] Calmodulin-like skin protein: a new marker of keratinocyte differentiation
[MarkerReference:9728054] Characterization and expression analysis of the Spink5 gene, the mouse ortholog of the defective gene in Netherton syndrome
[MarkerReference:9728022] KLK5 [cytosol] Kallikrein-related peptidase 5 functions in proteolytic processing of profilaggrin in cultured human keratinocytes
[MarkerReference:9728017] "Activated" keratinocyte phenotype is unifying feature in conditions which predispose to squamous cell carcinoma of the skin
[MarkerReference:9727996] Expression of keratin 1, keratin 10, desmoglein 1 and desmocollin 1 in the epidermis: possible downregulation by interleukin-4 and interleukin-13 in atopic dermatitis
[MarkerReference:9727997] Epidermal differentiation: the bare essentials
[MarkerReference:9839578] Identification of novel keratinocyte-secreted peptides dermokine-alpha/-beta and a new stratified epithelium-secreted protein gene complex on human chromosome 19q13.1
[MarkerReference:9728025] KLK7 [cytosol] LEKTI is localized in lamellar granules, separated from KLK5 and KLK7, and is secreted in the extracellular spaces of the superficial stratum granulosum
[MarkerReference:9728035] PRSS3 [tertiary granule lumen] Keratinocyte-specific mesotrypsin contributes to the desquamation process via kallikrein activation and LEKTI degradation
[MarkerReference:9839553] Identification of novel keratinocyte-secreted peptides dermokine-alpha/-beta and a new stratified epithelium-secreted protein gene complex on human chromosome 19q13.1
[MarkerReference:9727980] Expression of loricrin in skin disorders
[MarkerReference:9728013] HOPX [nucleoplasm] Homeodomain-only protein HOP is a novel modulator of late differentiation in keratinocytes
[MarkerReference:9839567] Identification of novel keratinocyte-secreted peptides dermokine-alpha/-beta and a new stratified epithelium-secreted protein gene complex on human chromosome 19q13.1
[MarkerReference:9839597] Multiple epidermal connexins are expressed in different keratinocyte subpopulations including connexin 31
[MarkerReference:9732200] FABP5 [cytosol] A histological and immunohistochemical study on chronic irritant contact dermatitis
[MarkerReference:9839626] Markers for Ca⁺⁺ -induced terminal differentiation of keratinocytes in vitro under defined conditions
[MarkerReference:9839497] Functional expression of AQP3 in human skin epidermis and reconstructed epidermis

maxDepth 2

modified [InstanceEdit:9839636] Orlic-Milacic, Marija, 2023年07月07日

name

keratinocyte of granulosum layer of epidermis
keratinocyte of skin epidermis stratum granulosum

organ [Anatomy:9725577] skin of body

producedByEvent

[CellDevelopmentStep:R-HSA-9727359] Keratinocyte of spinosum layer differentiates into keratinocyte of granulosum layer in interfollicular epidermis - Homo sapiens

proteinMarker

schemaClass Cell

species

[Species:48887] Homo sapiens

stId R-HSA-9727357

tissue [Anatomy:9725551] skin epidermis

tissueLayer [Anatomy:9727362] stratum granulosum of epidermis

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