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Schema
>
CellDevelopmentStep
>
Entries
Keratinocyte stem cell differentiates into transit amplifying cell in the basal layer of interfollicular epidermis
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authored
[InstanceEdit:9839035] Orlic-Milacic, Marija, 2023年06月29日
category
transition
compartment
[Compartment:984] extracellular region
created
[InstanceEdit:9725578] Orlic-Milacic, Marija, 2021年03月29日
dbId
9725621
displayName
Keratinocyte stem cell differentiates into transit amplifying cell in the basal layer of interfollicular epidermis
edited
[InstanceEdit:9863489] Orlic-Milacic, Marija, 2024年02月29日
eventOf
[CellLineagePath:R-HSA-9725554] Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin - Homo sapiens
followingEvent
[CellDevelopmentStep:R-HSA-9727354] Transit-amplifying cell of basal layer differentiates into keratinocyte of spinosum layer in interfollicular epidermis - Homo sapiens
goBiologicalProcess
[GO_BiologicalProcess:528093] keratinocyte development
input
[Cell:R-HSA-9725559] keratinocyte stem cell of skin epidermis basal layer
isChimeric
false
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:9732158] Epithelial stem cells in vivo
[LiteratureReference:9732141] Designer skin: lineage commitment in postnatal epidermis
[LiteratureReference:9725572] Role of melanoma chondroitin sulphate proteoglycan in patterning stem cells in human interfollicular epidermis
[LiteratureReference:9731158] Single-cell expression profiling of human epidermal stem and transit-amplifying cells: Lrig1 is a regulator of stem cell quiescence
[LiteratureReference:9731166] Stimulation of human epidermal differentiation by delta-notch signalling at the boundaries of stem-cell clusters
[LiteratureReference:9731952] Identification and isolation of candidate human keratinocyte stem cells based on cell surface phenotype
[LiteratureReference:9725604] Enrichment and identification of human 'fetal' epidermal stem cells
[LiteratureReference:9725610] [Epidermal growth factor induce the epithelial stem cell island formation in the regenerated epidermis]
[LiteratureReference:9731947] Dual Role of alpha6beta4 integrin in epidermal tumor growth: tumor-suppressive versus tumor-promoting function
[LiteratureReference:9725624] The type I keratin 19 possesses distinct and context-dependent assembly properties
[LiteratureReference:9725553] Numb Expression Contributes to the Maintenance of an Undifferentiated State in Human Epidermis
[LiteratureReference:9725580] p63 expression in normal skin and usual cutaneous carcinomas
[LiteratureReference:9732151] Desmosomal proteins, including desmoglein 3, serve as novel negative markers for epidermal stem cell-containing population of keratinocytes
[LiteratureReference:9732145] Stem cells of the corneal epithelium lack connexins and metabolite transfer capacity
[LiteratureReference:9732156] Epidermal stem cells do not communicate through gap junctions
[LiteratureReference:9732144] Long-term expansion of human functional epidermal precursor cells: promotion of extensive amplification by low TGF-beta1 concentrations
[LiteratureReference:9732178] Targeted disruption of LIG-1 gene results in psoriasiform epidermal hyperplasia
[LiteratureReference:9727376] Epidermal differentiation: the bare essentials
[LiteratureReference:9839467] Yes-associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin
[LiteratureReference:9839473] Yap1 acts downstream of ?-catenin to control epidermal proliferation
[LiteratureReference:9839476] Yap controls stem/progenitor cell proliferation in the mouse postnatal epidermis
[LiteratureReference:9839484] PanglaoDB: a web server for exploration of mouse and human single-cell RNA sequencing data
[LiteratureReference:9820674] CellMarker 2.0: an updated database of manually curated cell markers in human/mouse and web tools based on scRNA-seq data
[LiteratureReference:9861113] Single-cell RNA sequencing of human epidermis identifies Lunatic fringe as a novel regulator of the stem cell compartment
maxDepth
1
modified
[InstanceEdit:9863524] Orlic-Milacic, Marija, 2024年03月01日
name
Keratinocyte stem cell differentiates into transit amplifying cell in the basal layer of interfollicular epidermis
output
[Cell:R-HSA-9725625] transit-amplifying cell of epidermis basal layer
regulatedBy
[PositiveRegulation:9725602] Positive regulation by 'EGF [extracellular region]'
releaseDate
2024年03月27日
requiredInputComponent
[EntityWithAccessionedSequence:R-HSA-179837] EGFR [plasma membrane] - Homo sapiens
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:9861092] Ganier, Clarisse, 2024年02月13日
schemaClass
CellDevelopmentStep
species
[Species:48887] Homo sapiens
stId
R-HSA-9725621
summation
[Summation:9732161] The keratinocyte stem cells differentiate into keratinocytes...
tissue
[Anatomy:9725551] skin epidermis
updateTrackers
[UpdateTracker:9953672] Update Tracker - [CellDevelopmentStep:9725621] Keratinocyte stem cell differentiates into transit amplifying cell in the basal layer of interfollicular epidermis - v93:[modifyText]
Referrals
(updatedInstance)
[UpdateTracker:9953672] Update Tracker - [CellDevelopmentStep:9725621] Keratinocyte stem cell differentiates into transit amplifying cell in the basal layer of interfollicular epidermis - v93:[modifyText]
(precedingEvent)
[CellDevelopmentStep:R-HSA-9727354] Transit-amplifying cell of basal layer differentiates into keratinocyte of spinosum layer in interfollicular epidermis
(hasEvent)
[CellLineagePath:R-HSA-9725554] Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
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