Reactome Pathway Database

Schema > EntityWithAccessionedSequence > Entries

EML4(1-780)-ALK(1058-1620) fusion [cytosol] Show undefined attributes

compartment

[Compartment:70101] cytosol

componentOf

created [InstanceEdit:9716114] Rothfels, Karen, 2021年02月19日

crossReference

[DatabaseIdentifier:11944945] Mondo:0005233

dbId 9716119

disease

[Disease:1247848] non-small cell lung carcinoma

displayName EML4(1-780)-ALK(1058-1620) fusion [cytosol]

endCoordinate 780

hasModifiedResidue

[FragmentInsertionModification:9716094] Insertion of residues 1058 to 1620 at 781 from UniProt:Q9UM73 ALK

inDisease true

literatureReference

[LiteratureReference:9648139] Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer

maxDepth 1

memberOf

[CandidateSet:R-HSA-9700080] ALK fusion proteins [cytosol] - Homo sapiens

name

EML4(1-780)-ALK(1058-1620) fusion
Echinoderm microtubule-associated protein-like 4
EMAL4_HUMAN
EXON21-EXON 20
variant 2

referenceEntity [ReferenceGeneProduct:uniprot:Q9HC35] UniProt:Q9HC35 EML4

referenceType ReferenceGeneProduct

schemaClass EntityWithAccessionedSequence

species [Species:48887] Homo sapiens

stId R-HSA-9716119

startCoordinate 1

Referrals

(hasMember)

[CandidateSet:R-HSA-9700080] ALK fusion proteins [cytosol]

(hasComponent)

[Complex:R-HSA-9724104] EML4(1-780)-ALK(1058-1620) fusion dimer [cytosol]

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