Reactome Pathway Database

Schema > EntityWithAccessionedSequence > Entries

CBL E366_Q409del [cytosol] Show undefined attributes

compartment

[Compartment:70101] cytosol

created [InstanceEdit:9706180] Rothfels, Karen, 2020年11月04日

crossReference

dbId 9706179

disease

[Disease:9630839] acute myeloid leukemia

displayName CBL E366_Q409del [cytosol]

endCoordinate 906

hasModifiedResidue

[FragmentDeletionModification:9706026] Deletion of residues 366 to 409

inDisease true

literatureReference

[LiteratureReference:9706115] Novel c-CBL and CBL-b ubiquitin ligase mutations in human acute myeloid leukemia
[LiteratureReference:9706063] CBL exon 8/9 mutants activate the FLT3 pathway and cluster in core binding factor/11q deletion acute myeloid leukemia/myelodysplastic syndrome subtypes

maxDepth 1

memberOf

[CandidateSet:R-HSA-9706222] CBL mutants [cytosol] - Homo sapiens

modified [InstanceEdit:9832438] Orlic-Milacic, Marija, 2023年04月01日

name

CBL E366_Q409del
CBL E3 ubiquitin protein ligase
Signal transduction protein CBL
Proto-oncogene c-CBL
Casitas B-lineage lymphoma proto-oncogene
del exon 8

referenceEntity [ReferenceGeneProduct:uniprot:P22681] UniProt:P22681 CBL

referenceType ReferenceGeneProduct

schemaClass EntityWithAccessionedSequence

species [Species:48887] Homo sapiens

stId R-HSA-9706179

startCoordinate 1

updateTrackers

[UpdateTracker:9905515] Update Tracker - [EntityWithAccessionedSequence:9706179] CBL E366_Q409del [cytosol] - v85:[modifyName]

Referrals

(updatedInstance)

[UpdateTracker:9905515] Update Tracker - [EntityWithAccessionedSequence:9706179] CBL E366_Q409del [cytosol] - v85:[modifyName]

(hasMember)

[CandidateSet:R-HSA-9706222] CBL mutants [cytosol]

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