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Active ALK dimer binds IRS1 Show undefined attributes

authored

[InstanceEdit:9725664] Rothfels, Karen, 2021年03月30日

category binding

compartment

created [InstanceEdit:9700157] Rothfels, Karen, 2020年09月14日

dbId 9700156

displayName Active ALK dimer binds IRS1

edited

[InstanceEdit:9725664] Rothfels, Karen, 2021年03月30日

eventOf

[Pathway:R-HSA-201556] Signaling by ALK - Homo sapiens

followingEvent

[Reaction:R-HSA-9700168] Active ALK phosphorylates IRS1 - Homo sapiens

input

isChimeric false

isInDisease false

isInferred false

literatureReference

maxDepth 1

modified [InstanceEdit:10680101] Weiser, Joel, 2025年08月27日

name

Active ALK dimer binds IRS1

orthologousEvent

output

[Complex:R-HSA-9699993] Active ALK:IRS1 [plasma membrane]

precedingEvent

[Reaction:R-HSA-201521] ALK autophosphorylation - Homo sapiens

previousReviewStatus [ReviewStatus:9821384] two stars

releaseDate 2021年06月09日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-9700156

summation

[Summation:9700158] Phosphorylated tyrosine 1096 is the docking site for IRS1 on...

updateTrackers

[UpdateTracker:9853278] Update Tracker - [Reaction:9700156] Active ALK dimer binds IRS1 - v87:[addLiteratureReference, add_removeInput, modifyText]

Referrals

(updatedInstance)

[UpdateTracker:9853278] Update Tracker - [Reaction:9700156] Active ALK dimer binds IRS1 - v87:[addLiteratureReference, add_removeInput, modifyText]

(hasEvent)

[Pathway:R-HSA-201556] Signaling by ALK

(precedingEvent)

[Reaction:R-HSA-9700168] Active ALK phosphorylates IRS1

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