Reactome Pathway Database

Schema > EntityWithAccessionedSequence > Entries

EML4(1-223)insKMSTREKNSQV-ALK(1059-1620) fusion [cytosol] Show undefined attributes

compartment

[Compartment:70101] cytosol

componentOf

created [InstanceEdit:9699845] Rothfels, Karen, 2020年09月14日

crossReference

dbId 9699813

disease

[Disease:1247848] non-small cell lung carcinoma

displayName EML4(1-223)insKMSTREKNSQV-ALK(1059-1620) fusion [cytosol]

endCoordinate 223

hasModifiedResidue

[FragmentInsertionModification:9699847] Insertion of residues 1059 to 1620 at 224 from UniProt:Q9UM73 ALK
[FragmentReplacedModification:9699846] Replacement of residues 223 to 223 by EKMSTREKNSQV

inDisease true

literatureReference

maxDepth 1

memberOf

[CandidateSet:R-HSA-9700080] ALK fusion proteins [cytosol] - Homo sapiens

modified [InstanceEdit:9832525] Orlic-Milacic, Marija, 2023年04月02日

name

EML4(1-223)insKMSTREKNSQV-ALK(1059-1620) fusion
Echinoderm microtubule-associated protein-like 4
EMAL4_HUMAN
variant 3b
Exon 6 - Exon 20

referenceEntity [ReferenceGeneProduct:uniprot:Q9HC35] UniProt:Q9HC35 EML4

referenceType ReferenceGeneProduct

schemaClass EntityWithAccessionedSequence

species [Species:48887] Homo sapiens

stId R-HSA-9699813

startCoordinate 1

updateTrackers

[UpdateTracker:9905394] Update Tracker - [EntityWithAccessionedSequence:9699813] EML4(1-223)insKMSTREKNSQV-ALK(1059-1620) fusion [cytosol] - v85:[modifyName]

Referrals

(updatedInstance)

[UpdateTracker:9905394] Update Tracker - [EntityWithAccessionedSequence:9699813] EML4(1-223)insKMSTREKNSQV-ALK(1059-1620) fusion [cytosol] - v85:[modifyName]

(hasMember)

[CandidateSet:R-HSA-9700080] ALK fusion proteins [cytosol]

(hasComponent)

[Complex:R-HSA-9699976] EML4(1-223)insKMSTREKNSQV -ALK(1059-1620) fusion dimer [cytosol]

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