Reactome Pathway Database

Schema > EntityWithAccessionedSequence > Entries

p-6Y-FLT3 L610_E611insCSSDNEYFYVDFREYEYDLKWEFPRENL [plasma membrane] Show undefined attributes

compartment

[Compartment:876] plasma membrane

componentOf

created [InstanceEdit:9696040] Rothfels, Karen, 2020年07月17日

crossReference

dbId 9696047

disease

displayName p-6Y-FLT3 L610_E611insCSSDNEYFYVDFREYEYDLKWEFPRENL [plasma membrane]

endCoordinate 993

hasModifiedResidue

inDisease true

literatureReference

[LiteratureReference:9696007] FLT3 internal tandem duplication mutations associated with human acute myeloid leukemias induce myeloproliferative disease in a murine bone marrow transplant model
[LiteratureReference:9697896] Tandem-duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3-dependent cell lines

maxDepth 1

modified [InstanceEdit:9832501] Orlic-Milacic, Marija, 2023年04月01日

name

p-6Y-FLT3 L610_E611insCSSDNEYFYVDFREYEYDLKWEFPRENL
Npos
Mut1

referenceEntity [ReferenceGeneProduct:uniprot:P36888] UniProt:P36888 FLT3

referenceType ReferenceGeneProduct

schemaClass EntityWithAccessionedSequence

species [Species:48887] Homo sapiens

stId R-HSA-9696047

startCoordinate 27

updateTrackers

[UpdateTracker:9905390] Update Tracker - [EntityWithAccessionedSequence:9696047] p-6Y-FLT3 L610_E611insCSSDNEYFYVDFREYEYDLKWEFPRENL [plasma membrane] - v85:[modifyName, removeHasModifiedResidue]

Referrals

(updatedInstance)

[UpdateTracker:9905390] Update Tracker - [EntityWithAccessionedSequence:9696047] p-6Y-FLT3 L610_E611insCSSDNEYFYVDFREYEYDLKWEFPRENL [plasma membrane] - v85:[modifyName, removeHasModifiedResidue]

(hasComponent)

[Complex:R-HSA-9696092] p-6Y FLT3 L610_E611insC22DNEYFYVDFREYEYDLKWEFPRENL dimer [plasma membrane]

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