Reactome Pathway Database

Schema > EntityWithAccessionedSequence > Entries

FLT3 Y591_V592insVDFREDREHH [plasma membrane] Show undefined attributes

compartment

[Compartment:876] plasma membrane

componentOf

[Complex:R-HSA-9696078] FLT3 Y591_V592insVDFREDREHH dimer [plasma membrane] - Homo sapiens
[Complex:R-HSA-9696078] FLT3 Y591_V592insVDFREDREHH dimer [plasma membrane] - Homo sapiens

created [InstanceEdit:9696040] Rothfels, Karen, 2020年07月17日

crossReference

dbId 9696043

disease

displayName FLT3 Y591_V592insVDFREDREHH [plasma membrane]

endCoordinate 993

hasModifiedResidue

[FragmentReplacedModification:9696019] Replacement of residues 591 to 592 by YVDFRREDREHHV

inDisease true

literatureReference

[LiteratureReference:9649423] Flt3 mutations from patients with acute myeloid leukemia induce transformation of 32D cells mediated by the Ras and STAT5 pathways

maxDepth 1

memberOf

[CandidateSet:R-HSA-9691152] juxtamembrane domain mutants of FLT3 [plasma membrane] - Homo sapiens

modified [InstanceEdit:9832478] Orlic-Milacic, Marija, 2023年04月01日

name

FLT3 Y591_V592insVDFREDREHH
ITD4

referenceEntity [ReferenceGeneProduct:uniprot:P36888] UniProt:P36888 FLT3

referenceType ReferenceGeneProduct

schemaClass EntityWithAccessionedSequence

species [Species:48887] Homo sapiens

stId R-HSA-9696043

startCoordinate 27

updateTrackers

[UpdateTracker:9905431] Update Tracker - [EntityWithAccessionedSequence:9696043] FLT3 Y591_V592insVDFREDREHH [plasma membrane] - v85:[removeHasModifiedResidue]

Referrals

(updatedInstance)

[UpdateTracker:9905431] Update Tracker - [EntityWithAccessionedSequence:9696043] FLT3 Y591_V592insVDFREDREHH [plasma membrane] - v85:[removeHasModifiedResidue]

(hasMember)

[CandidateSet:R-HSA-9691152] juxtamembrane domain mutants of FLT3 [plasma membrane]

(hasComponent)

[Complex:R-HSA-9696078] FLT3 Y591_V592insVDFREDREHH dimer [plasma membrane]

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